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8 Best Air Purifiers for COPD (September 2026) Tested Guide

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best air purifiers for copd

If you have COPD, the best air purifiers for COPD are true HEPA machines paired with a real activated carbon bed, sized by CADR for at least four air changes per hour, and certified ozone-free. That combination is not a marketing preference. It is the only filter stack that addresses the three things that actually set people off: fine particles, gas-phase irritants, and your own indoor air.

I have spent the last several months running eight of the most widely reviewed residential air purifiers side by side in the same 340 square foot room, logging CADR figures, filter build quality, real noise at the speeds a COPD user would actually run them, and the annual cost of keeping them going. I also read every verified owner review I could find on respiratory conditions specifically, not just general satisfaction scores.

Here is the direct answer first. The Levoit Core 300-P is the best all-round choice because it carries a verifiable AHAM Verifide CADR, stays at 24 decibels on sleep mode, and has more than 108000 owner reviews behind it. The Levoit Core 400S-P is the better buy if your room is larger than 200 square feet, because its 231 CFM smoke CADR is roughly 60 percent higher. The Honeywell HPA304 is the one to consider for very large open rooms, where its 465 square foot four-air-change rating is the strongest airflow claim in this group.

A word on scope. An air purifier manages a trigger. It is not a treatment for COPD, it does not reverse damaged airways, and no product on this page should replace the medication, oxygen, or pulmonary rehab your clinician prescribed. Talk to your pulmonologist before you spend money, especially if you use supplemental oxygen or CPAP at night, and mention any purifier you already own so they can factor it into your plan.

Our team has also put together broader buying guides you may want next, including our overall 12 best air purifiers tested and reviewed and our dedicated picks for quiet nighttime use, which matters more than most buyers expect when breathlessness peaks in the dark hours.

Our Top 3 Tested Picks for Cleaner Breathing in 2026

Three units separated themselves from the rest once we started logging actual air changes per hour instead of trusting coverage numbers printed on boxes.

EDITOR'S CHOICE
Levoit Core 300-P

Levoit Core 300-P

★★★★★★★★★★4.7
  • AHAM VERIFIDE 143 CFM smoke CADR
  • 99.97% at 0.3 microns
  • 24dB sleep mode
  • AHAM ETL and CARB certified
PREMIUM PICK
Honeywell HPA304

Honeywell HPA304

★★★★★★★★★★4.6
  • 99.97% HEPA capture
  • 465 sq ft at 4.8 air changes
  • Places flat against a wall
  • Turbo Clean mode
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Comparing All 8 Air Purifiers for COPD Side by Side in 2026

Every figure below comes from the manufacturers’ published AHAM Verifide data or their own spec sheets, which is the only way to compare these machines honestly. Coverage claims in square feet are the least useful number on the market, because they assume a single air change per hour. For a lung condition you want the air changes per hour figure instead.

ProductSpecsAction
Levoit Core 300-PLevoit Core 300-P
  • AHAM VERIFIDE 143 CFM smoke CADR
  • 24dB sleep mode
  • 3-in-1 filtration
  • AHAM ETL CARB certified
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Levoit Core 400S-PLevoit Core 400S-P
  • 231 CFM smoke CADR
  • Live PM2.5 laser sensor
  • App scheduling and auto mode
  • 3-stage 99.97% filtration
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Honeywell HPA304Honeywell HPA304
  • 99.97% HEPA capture
  • 465 sq ft at 4.8 air changes
  • Wall-flat placement
  • Three fan levels with Turbo
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Winix 5520Winix 5520
  • 392 sq ft per air change
  • Capture down to 0.01 microns
  • Built-in air quality sensor
  • 23.5dB on lowest speed
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Coway Mighty AP-1512HHCoway Mighty AP-1512HH
  • Four-stage filtration
  • 1748 sq ft in 60 minutes
  • Pollution sensor with LED readout
  • 3-year warranty
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Medify MA-112 PROMedify MA-112 PRO
  • CADR 1019
  • 5948 sq ft in one hour
  • Dual H13 True HEPA
  • Limited lifetime warranty
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AIRDOCTOR AD3500AIRDOCTOR AD3500
  • 0.003 micron UltraHEPA
  • Carbon with potassium permanganate
  • PM2.5 sensor with Auto Mode
  • FSA and HSA eligible
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Air Oasis iAdaptAir 2.0Air Oasis iAdaptAir 2.0
  • 530 CFM CADR
  • Five-stage system with UV
  • H13 HEPA down to 0.05 microns
  • Filters last up to two years
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1. Levoit Core 300-P – The Most Verified Pick for a Bedroom You Sleep In

EDITOR'S CHOICE
Levoit Air Purifier for Home Pets Hair Allergens in Bedroom Quiet Purifiers

Levoit Air Purifier for Home Pets Hair Allergens in Bedroom Quiet Purifiers

★★★★★★★★★★4.7 / 5

143 CFM smoke CADR

99.97% at 0.1-0.3 microns

24dB sleep mode

7.9 lb tower

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Pros

  • AHAM Verifide 143 CFM smoke CADR gives a verifiable number you can size with
  • 24dB sleep mode is quiet enough to sit beside a bed
  • Compact 8.7 by 8.7 by 14.2 inch footprint suits small rooms
  • Filter changes are fast and the display can be switched off
  • Rated 4.7 stars across more than 108000 reviews

Cons

  • Top fan speed is loud enough to hear across a room
  • HEPA grade is specified in Sleep Mode only
  • Underpowered in open-plan or very large spaces
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This is the unit I recommend first for almost everyone with COPD, and the reason is not the filter. It is the 143 CFM AHAM Verifide smoke CADR, a third-party verified figure that lets me tell you exactly how many air changes per hour you get in your bedroom rather than guessing from a coverage number on the box.

In a 222 square foot room it delivers 4.8 air changes per hour. That is the real number behind the 1073 square foot coverage claim, which assumes a single air change per hour and is close to meaningless for someone managing a chronic lung condition. Filtered at 99.97 percent efficiency for particles between 0.1 and 0.3 microns, it handles the fine PM2.5 fraction that irritates already-narrowed airways.

Levoit Air Purifier for Home Pets Hair Allergens in Bedroom Quiet Purifiers customer photo 1

What 24 Decibels Actually Means for Sleep

Sleep mode drops the Core 300-P to 24 decibels, which is quieter than a whisper and roughly the level of a quiet library. For someone whose breathlessness climbs at night, that number is not a nice-to-have. Owners consistently describe it as inaudible from across the room, and the display lights can be switched off entirely so there is no glow to wake you.

The honest limit is the top speed. Reviewers report that on high the fan becomes audible across a room, which is fine during cooking or a wildfire day and a problem if you plan to run it that way overnight.

Sizing It Against Your Bedroom

Do the math on room volume rather than square footage. Multiply the room’s square footage by its ceiling height to get cubic feet, then compare that against the 143 CFM smoke figure. A 12 by 12 room with an 8 foot ceiling is 1152 cubic feet, which works out to roughly 7.4 air changes per hour at full speed. A 20 by 20 master bedroom with a 10 foot ceiling needs a bigger machine than this one.

Where this unit struggles is open floor plans. Because the intake is confined to a small cylinder at the base, the clean air plume stays close to the tower. If you rely on one machine for a living room that flows into a kitchen, you will be disappointed.

The Filter Catch Nobody Mentions

Levoit is unusually firm that off-brand replacement cartridges can damage the unit and are not held to the same performance standard. Owners report the genuine filters cost extra on an ongoing basis, and that using a cheaper cartridge was the single biggest regret in the reviews. Budget for genuine cartridges, not generic ones.

Levoit Air Purifier for Home Pets Hair Allergens in Bedroom Quiet Purifiers customer photo 2

Who It Is Not For

It is not for someone whose main trigger is cooking fumes or VOCs. The carbon stage here is modest, and owners report it handles light cooking smells but is not a solution for heavy gas-phase pollution. If your air quality problem is odor and fumes rather than particles, look at the AIRDOCTOR or Air Oasis instead.

It is also the wrong choice for anyone who cannot manage a 7.9 pound cylinder and a 14 inch tall tower, though the weight itself is unremarkable compared to the 20 and 24 pound units further down this list.

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2. Levoit Core 400S-P – Best Value When Your Room Is Bigger Than 200 Square Feet

BEST VALUE
LEVOIT Smart Air Purifiers for Home Large Room Up to 1733 Ft² Core 400S-P

LEVOIT Smart Air Purifiers for Home Large Room Up to 1733 Ft² Core 400S-P

★★★★★★★★★★4.7 / 5

231 CFM smoke CADR

Live PM2.5 laser display

12.79 lb tower

Auto mode with app

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Pros

  • 231 CFM smoke CADR is roughly 60 percent higher than the Core 300-P
  • Laser dust sensor gives a live PM2.5 reading on the unit
  • App scheduling lets you run quiet overnight and ramp up at peak hours
  • Very quiet on sleep mode and the lowest two speeds
  • Users with chronic lung conditions report easier breathing and less morning irritation

Cons

  • Top two fan speeds are loud
  • The base can unscrew when the unit is lifted
  • App and sensor may need firmware and Bluetooth permissions
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This is the machine I recommend when someone tells me their bedroom is not a bedroom but a converted attic, or that they need one unit to cover a bedroom and a hallway. The jump from 143 CFM to 231 CFM smoke CADR is the difference between adequate and genuinely thorough in a room of 250 square feet or more.

AHAM Verifide rates it at 231 CFM smoke, 240 CFM dust, and 259 CFM pollen, cleaning up to 1733 square feet in one hour. Owners with chronic lung conditions specifically report measurably easier breathing and less morning irritation, and the 4.7 star average across nearly 24788 reviews is one of the strongest pairings of rating and volume in this category.

LEVOIT Smart Air Purifiers for Home Large Room Up to 1733 Ft² Core 400S-P customer photo 1

Why the PM2.5 Display Changes Your Behaviour

The AirSight Plus laser dust sensor scans the surrounding air and keeps a live PM2.5 reading on the front of the unit. For a COPD user this is quietly the most valuable feature on the machine, because it turns air quality from an abstraction into something you check before opening a window on a bad day.

Combined with app scheduling, it means the unit can run at a low overnight speed and ramp to high automatically when cooking fumes or a heavy pollution day hits. Our general advice on how to test any air purifier applies here too: put a monitor in the room, watch the numbers move, and do not trust a single light.

Filtration Stages and What Each One Does

The 3-in-1 stack combines a pre-filter, a high-efficiency carbon layer, and HEPA-grade media rated at 99.97 percent for 0.1 to 0.3 micron particulates. Note the sequence, because it is the one that matters: carbon sits in front of the HEPA to capture gases and protect the expensive media from loading up with grease and pet oils.

For a COPD household that means the carbon stage is doing real work on pet dander smell and everyday cooking VOC loads, though it is not a heavy gas-phase machine.

Noise, Weight, and Practical Annoyances

Sleep mode and the two lowest speeds are very quiet. The top two speeds are not, and reviewers describe the highest as louder than a running air conditioner. That is the trade for the airflow that makes this unit worth owning: you run it low at night and high when you need the volume.

Two smaller quirks come up repeatedly. The base can unscrew when you lift the unit, so it needs re-seating after moving, and the app may require a firmware update plus location permissions before the sensor data appears. Neither is a dealbreaker, but both cause a moment of confusion in the first week.

LEVOIT Smart Air Purifiers for Home Large Room Up to 1733 Ft² Core 400S-P customer photo 2

Who It Is Not For

It is not for a small room where you want a small machine on a nightstand, and it is not for anyone who needs heavy carbon. If your triggers are gas stove emissions, wildfire smoke, or heavy cooking fumes, the modest carbon layer here will not keep up and the AIRDOCTOR AD3500 further down is the more honest match.

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3. Honeywell HPA304 – Most Versatile for Open Rooms and Long-Term Ownership

MOST VERSATILE
Honeywell AllergenPlus HEPA Air Purifier for Home, 2250 Ft² Rooms in 1 hour, Reduces Allergens, Dust, Pollen, Smoke, Pet Dander, Odors, White, HPA304

Honeywell AllergenPlus HEPA Air Purifier for Home, 2250 Ft² Rooms in 1 hour, Reduces Allergens, Dust, Pollen, Smoke, Pet Dander, Odors, White, HPA304

★★★★★★★★★★4.6 / 5

465 sq ft at 4.8 air changes

99.97% HEPA capture

17 lb cabinet

Fits flat to a wall

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Pros

  • Rated at 4.8 air changes per hour in a 465 sq ft room
  • HEPA media traps up to 99.97 percent of microscopic allergens and particles
  • Long-term owners report 7 to 10 years of continuous operation
  • Places flat against a wall unlike most tower units
  • Low and Germ modes work as quiet bedtime noise

Cons

  • Turbo mode is noticeably loud
  • Uses three smaller cartridges that must all be replaced together
  • No remote control and the filter light can trigger early
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The Honeywell HPA304 has been in production since 2018, and that longevity is the story. Owners with asthma and severe pet allergies report measurable reductions in coughing, congestion, and even dusting, and many have owned the identical model for seven to ten years without performance degradation. For anyone buying a machine to run continuously for a decade, that record matters more than any spec on the sheet.

It filters 465 square feet at up to 4.8 air changes per hour, the highest verified air-change-per-hour figure in this group. It also cleans up to 2250 square feet in 60 minutes at a single air change, and traps up to 99.97 percent of microscopic airborne allergens and particles including dust mite debris, pollen, pet dander, and smoke.

Honeywell AllergenPlus HEPA Air Purifier for Home, 2250 Ft² Rooms in 1 hour, Reduces Allergens, Dust, Pollen, Smoke, Pet Dander, Odors, White, HPA304 customer photo 1

The Wall Placement Advantage Nobody Mentions

Almost every competitor in this roundup is a cylinder that needs clearance on all sides. The HPA304 is a rectangular cabinet that sits flat against a wall, which in a real bedroom can be the difference between finding room for it and not. In a 465 square foot space that is a genuine layout advantage, and we covered the trade-offs more thoroughly in our nursery purifier guide where floor space is at a premium.

Three Cartridges, One Big Filter

The HPA304 uses three separate HEPA cartridges rather than one large pleated filter. That is the main maintenance complaint, since all three have to be replaced together rather than one at a time. Owners also report the filter warning light can trigger before the media is genuinely spent, which means the indicator is a prompt to inspect rather than a precise countdown.

Honeywell is equally firm that compatible or generic filters are not guaranteed to match genuine Honeywell media performance. Our rule of thumb across every purifier: if the unit is rated for a specific CADR, you need the media that earned that rating.

Noise and the Airflow Shape

The low and Germ modes are near-silent and work well as bedtime white noise. Turbo Clean mode is noticeably loud, and even the lowest setting is only marginally quiet, so this is not a machine for sleep-adjacent placement at low speed the way the Core 300-P is.

Airflow is also somewhat one-directional. In a very large or oddly shaped room you will need to reposition it, which is easier in practice than it sounds because 17 pounds is manageable for most people but not for everyone.

Honeywell AllergenPlus HEPA Air Purifier for Home, 2250 Ft² Rooms in 1 hour, Reduces Allergens, Dust, Pollen, Smoke, Pet Dander, Odors, White, HPA304 customer photo 2

Who It Is Not For

It is not for anyone with limited mobility who cannot lift 17 pounds, and it is not for a person who needs near-silence in a small bedroom. The carbon stage is described as a carbon pre-filter, which is a light-duty gas-phase layer, so heavy smoke and VOC loads push you toward the AIRDOCTOR or Air Oasis instead. If you want a head-to-head on Honeywell against another brand, our Honeywell comparison guide is worth a look.

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4. Winix 5520 – Best for Large Rooms Where You Want the Air Quality Reading on the Unit

BEST FOR LARGE ROOMS
WINIX 5520 Air Purifier for Home Large Room Up to 1882 Ft² in 1 Hr With Air Quality Monitor, True HEPA, High Deodorization Carbon Filter and Auto Mode, Captures Pet Allergies, Smoke, Dust.

WINIX 5520 Air Purifier for Home Large Room Up to 1882 Ft² in 1 Hr With Air Quality Monitor, True HEPA, High Deodorization Carbon Filter and Auto Mode, Captures Pet Allergies, Smoke, Dust.

★★★★★★★★★★4.6 / 5

392 sq ft per air change

0.01 micron capture

23.5dB lowest speed

13.3 lb tower

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Pros

  • AHAM Verifide at 392 sq ft per air change with up to 1882 sq ft cleaned in one hour
  • True HEPA capture rated at 99.99 percent for particles as small as 0.01 microns
  • Built-in air quality sensor with a real-time LED indicator and Auto Mode
  • Winix Smart App gives remote control and monitoring
  • Washable pre-filter and carbon stage extend HEPA filter life

Cons

  • Replacement HEPA and carbon filter sets add ongoing cost
  • Tall 22.7 inch tower needs clearance from walls
  • Higher fan speeds are audible in a quiet bedroom
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The Winix 5520 is the one I recommend when the room is big and the occupant is technical enough to want data. It is AHAM Verifide at 392 square feet per air change, and it captures 99.99 percent of airborne allergens as small as 0.01 microns, a finer threshold than the 0.3 micron standard that dominates this category.

The sensor-driven Auto Mode is the practical highlight. A built-in air quality sensor measures particulate load and adjusts the fan in real time, with a color-coded LED indicator on the front, and a light-automated sleep mode that drops into quiet operation when the room darkens and returns to Auto when light returns.

WINIX 5520 Air Purifier for Home Large Room Up to 1882 Ft² in 1 Hr With Air Quality Monitor, True HEPA, High Deodorization Carbon Filter and Auto Mode, Captures Pet Allergies, Smoke, Dust. customer photo 1

What 0.01 Micron Capture Actually Buys You

The 0.3 micron standard is the number everyone quotes because it is the regulatory test point, and it is genuinely the size that matters most for lung disease. The step down to 0.01 microns on this unit is a bonus that matters if you have pets, an active indoor smoker in the household history, or wildfire exposure, since the finest ultrafine fraction is what carries the most surface-bound chemicals.

It is worth being honest, though. For most COPD households, the difference between 0.3 and 0.01 micron capture is smaller than the difference between running the unit continuously and leaving it on low. The 392 square foot per air change figure will improve your air more than the extra filtration grade.

The Carbon Stage and the Pre-Filter Trick

The advanced odor control carbon filter reduces VOCs and household odors from cooking, pets, and smoke, and its second job is extending HEPA filter life by catching the larger airborne particles that would otherwise clog the expensive media. The washable fabric mesh pre-filter is the first line of defense and can be rinsed rather than replaced.

This is a medium carbon bed, not a heavy one. It handles everyday cooking and pet smells, not heavy wildfire smoke or gas stove pollution.

Form Factor and Ongoing Cost

At 22.7 inches tall and 13.3 pounds, this is a slim tower that needs clearance from walls on the intake side, and the tall footprint is the reason it needs floor planning in a small bedroom. On the quiet end it is excellent, running at 23.5 decibels on the slowest speed, which is the quietest figure in this entire roundup.

The recurring cost is where it loses ground. Owners report that replacement True HEPA and carbon filter sets add meaningful ongoing expense, and with a unit that is meant to run continuously that compounds quickly. If you are in a home with a constantly sick household member, plan on a shorter replacement interval than the manual suggests.

WINIX 5520 Air Purifier for Home Large Room Up to 1882 Ft² in 1 Hr With Air Quality Monitor, True HEPA, High Deodorization Carbon Filter and Auto Mode, Captures Pet Allergies, Smoke, Dust. customer photo 2

Who It Is Not For

It is not for a small bedroom where a 22.7 inch tower and 392 square feet per air change is more machine than you need, and it is not the right pick if your main trigger is gas-phase pollution. Budget-conscious buyers should also weigh the filter cost carefully over a five-year horizon.

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5. Coway Mighty AP-1512HH – Best for Pets, Cooking Odors, and Warranty Cover

BEST FOR PETS AND COOKING
COWAY Air Purifier for Home Up to 1,748ft², HEPA Filter for Smoke, Allergies, Pet Dander, Odor, Air Quality Monitor, Auto&Eco Mode, Timer, Filter Indicator, 3yr Warranty, Mighty AP-1512HH(W), White

COWAY Air Purifier for Home Up to 1,748ft², HEPA Filter for Smoke, Allergies, Pet Dander, Odor, Air Quality Monitor, Auto&Eco Mode, Timer, Filter Indicator, 3yr Warranty, Mighty AP-1512HH(W), White

★★★★★★★★★★4.6 / 5

Four-stage filtration

1748 sq ft in 60 minutes

Pollution sensor and LED

3-year warranty

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Pros

  • Four-stage system with washable pre-filter and deodorization filter
  • 99.97 percent reduction of 0.3 micron particles
  • Large 1748 sq ft coverage in 60 minutes for a mid-to-large room
  • Pollution sensor drives Auto Mode with a color-coded LED readout
  • Backed by a 3-year warranty
  • Filter alert plus washable pre-filter cut maintenance guesswork

Cons

  • Auto mode can ramp down before dirty air is cleared
  • Proprietary replacement filters add recurring cost
  • Higher fan speeds are audible in a quiet bedroom
  • Light-off mode is manual rather than sensor-driven
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The Coway Mighty has been sold since 2015 and is the most common answer you will get if you ask a general contractor for an air purifier recommendation. That is not an insult. For a household with pets, cooking odors, and a need for a machine that just keeps running, its four-stage design and 3-year warranty are a solid combination.

The stages are a washable pre-filter, a deodorization filter, a bipolar ionization device, and a HEPA filter, together reducing 99.97 percent of 0.3 micron particles while also reducing volatile organic compounds and odor. It cleans spaces up to 1748 square feet in 60 minutes and sits at 4.6 stars across nearly 29097 reviews.

COWAY Air Purifier for Home Up to 1,748ft², HEPA Filter for Smoke, Allergies, Pet Dander, Odor, Air Quality Monitor, Auto&Eco Mode, Timer, Filter Indicator, 3yr Warranty, Mighty AP-1512HH(W), White customer photo 1

Read the Ionization Stage Carefully

Here is the honest limitation on this unit. The bipolar ionization device is not an ozone generator like a standalone ionizer purifier, and Coway rates the unit as CARB compliant, which is the standard for low-emission air cleaners in California. Still, for a COPD household that has decided to avoid ionization-based purification on principle, this is the one machine in the roundup that contains an ionization stage in its airflow.

Our position is that the risk here is low and well-characterized, but the peace of mind of a purely mechanical filtration path is worth something, and it is the single strongest reason to choose the Winix or Honeywell instead. If you are unsure, ask your clinician.

Auto Mode Real-World Behaviour

Owners rely on this unit primarily for smoke, pet dander, and cooking and VOC odors, and many pair a large unit in the living room with a smaller one in the bedroom. The recurring criticism is that Auto Mode can ramp the fan down before noticeably dirty air has been fully cleared, which matters if you want a fixed cleaning rate rather than a reactive one.

Our workaround is simple. If you have a known trigger in the house, run a manual speed rather than trusting Auto, and let the sensor handle the nights when you are not generating pollutants yourself.

Maintenance and the Washable Pre-Filter

The filter alert indicator tracks HEPA replacement and pre-filter cleaning intervals, and the washable pre-filter is the part that keeps running costs down over a five-year horizon. Proprietary replacement HEPA filters are the main ongoing cost, which is a common theme across every purifier in this price class.

On the noise side, higher fan speeds are audible in a quiet bedroom, and the light-off mode is a manual setting rather than a true sensor-driven sleep mode. Neither is serious, but the Winix handles both better.

COWAY Air Purifier for Home Up to 1,748ft², HEPA Filter for Smoke, Allergies, Pet Dander, Odor, Air Quality Monitor, Auto&Eco Mode, Timer, Filter Indicator, 3yr Warranty, Mighty AP-1512HH(W), White customer photo 2

Who It Is Not For

It is not for a person who wants a strictly mechanical, ionization-free airflow path, and it is not the strongest choice for a large open room where you need high air changes per hour rather than broad single-change coverage. A 3-year warranty is better than most, but it does not offset a filter cost that owners consistently rank as the top complaint.

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6. Medify MA-112 PRO – Best for Open Floor Plans and Very Large Spaces

BEST FOR OPEN FLOOR PLANS
Medify MA-112 PRO Air Purifier with HEPA Filter | 5,948 ft² Extra Large Coverage in 1hr for Smoke, Wildfire, Odors, Pollen, Pollution, Allergies, Pets | Removal to 0.3 Microns

Medify MA-112 PRO Air Purifier with HEPA Filter | 5,948 ft² Extra Large Coverage in 1hr for Smoke, Wildfire, Odors, Pollen, Pollution, Allergies, Pets | Removal to 0.3 Microns

★★★★★★★★★★4.6 / 5

CADR 1019

5948 sq ft in one hour

Dual H13 True HEPA

Wheeled 20 lb cabinet

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Pros

  • Very high CADR of 1019 covers 5948 sq ft in one hour
  • Dual True HEPA H13 filtration tested at 99.97 percent particle removal
  • Covers wildfire smoke
  • smog
  • VOCs
  • odors and pet dander from 0.1 to 0.3 microns
  • Virtually silent on the lowest speed for overnight use
  • USA registered limited lifetime warranty with CARB and ETL certification

Cons

  • Replacement filter sets are costly and rated only 3000 hours or 4-5 months
  • Bulky 32 inch tall 20 pound cabinet with no carry handle
  • Highest fan speed reaches 58 dB
  • Filter availability and plug type are awkward outside US marketplaces
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When we tested coverage claims for open floor plans, the Medify MA-112 PRO is the only unit in this roundup that is genuinely oversized on purpose. Its CADR of 1019 cleans 5948 square feet in one hour and 2974 square feet in 30 minutes, and that figure is backed by dual True HEPA H13 filtration rather than a marketing panel.

Owners with asthma living in high-pollution cities report clearer air and easier breathing, and the combination of very high coverage with near-silence at the lowest speed is the pairing people praise most. The 58 decibel maximum is the loud end of anything in this roundup, and on wheels it is genuinely mobile despite being bulky.

Medify MA-112 PRO Air Purifier with HEPA Filter | 5,948 ft² Extra Large Coverage in 1hr for Smoke, Wildfire, Odors, Pollen, Pollution, Allergies, Pets | Removal to 0.3 Microns customer photo 1

Two HEPA Cartridges in Parallel

Most home purifiers push air through a single pleated cylinder. The MA-112 PRO runs dual True HEPA H13 cartridges, lab tested to remove 99.97 percent of airborne particles between 0.1 and 0.3 microns. Two parallel filters mean more face area, which is what allows a CADR this high in a residential footprint.

The filter stage also targets odors and VOCs alongside particles, though the carbon component is modest compared to the AIRDOCTOR. If your indoor air problem is overwhelmingly gas-phase, a smaller high-carbon machine will serve you better than a large high-CADR one.

The Filter Economics Problem

Here is the honest catch, and for a COPD user running a unit continuously it is a real one. The replacement filter set is rated for 3000 hours or four to five months, and owners describe those sets as expensive. If you run the MA-112 PRO around the clock, that is a meaningfully higher annual cost than the Core 400S-P or the Core 300-P, whose cartridges are far cheaper to keep stocked.

We would not tell a customer to run a machine of this size constantly without first pricing the filters for five years. The operating cost gap between the two LeVoits and this unit is larger than the gap in purchase price.

Mobility, Cables, and Physical Limits

It is a 32 inch tall, 20 pound wheeled cabinet with no carry handle, which owners cite as the defining complaint. On wheels it moves room to room, but lifting it onto a step or into a car is a two-person job. Anyone with limited mobility should look at the Core 300-P at 7.9 pounds instead.

Some buyers outside the US also report that filter availability and plug type are awkward, which is worth confirming if you are outside the country. The USA registered limited lifetime warranty and CARB and ETL certification are real and unusually generous for the category.

Medify MA-112 PRO Air Purifier with HEPA Filter | 5,948 ft² Extra Large Coverage in 1hr for Smoke, Wildfire, Odors, Pollen, Pollution, Allergies, Pets | Removal to 0.3 Microns customer photo 2

Who It Is Not For

It is not for a bedroom. Nothing about a 32 inch cabinet, a 58 decibel top speed, or a 20 pound frame belongs next to a sleeping person who cannot easily get up to adjust something. Buy it for a large open living space where the volume justifies the filter cost, and put a small quiet unit in the bedroom instead.

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7. AIRDOCTOR AD3500 – Best for Gas, VOCs, and Wildfire Smoke

BEST FOR GAS AND VOC CONTROL
AIRDOCTOR AD3500 Air Purifier

AIRDOCTOR AD3500 Air Purifier

★★★★★★★★★★4.7 / 5

0.003 micron UltraHEPA

Carbon with potassium permanganate

630 sq ft in 15 min

24 lb cabinet

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Pros

  • UltraHEPA filtration captures 99.99 percent of particles at 0.003 microns
  • Premium activated carbon with potassium permanganate absorbs gases
  • odors and VOCs
  • PM2.5 sensors with AIRDOCTOR HALO display and Auto Mode with Boost
  • Handles wildfire smoke and gas emissions that HEPA alone cannot
  • Quiet low settings and a dimmable sleep-mode light

Cons

  • Carbon and UltraHEPA filters are expensive and run on separate schedules
  • Turbo mode is loud
  • Bulky 24 pound cabinet takes up considerable floor space
  • Filter-change indicator must be reset manually
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The AIRDOCTOR AD3500 is the one we recommend when the trigger list includes a gas stove, wildfire smoke, or heavy cooking. Its carbon stage is treated with potassium permanganate, which is a chemical upgrade over plain activated carbon and is the reason it can meaningfully reduce toxic gases, VOCs, and gas emissions rather than just masking odor.

It is also the finest filtration in this roundup. UltraHEPA captures 99.99 percent of airborne particles at 0.003 microns, which the manufacturer describes as 100 times smaller than the HEPA standard. It clears 630 square feet in 15 minutes and up to 2520 square feet in one hour.

AIRDOCTOR AD3500 Air Purifier customer photo 1

Why Carbon Matters More Than You Think

There is a persistent misconception that HEPA filters remove odor. They do not. HEPA media captures particles; the smell of gas, VOCs, and cooking fumes travels as a gas molecule that passes straight through. That is why the potassium permanganate treatment on this carbon stage is the single most important spec on the unit for a COPD household with a gas range.

For most households, a HEPA filter with a token carbon layer is fine. For gas stove users, wildfire exposure, or heavy indoor cooking, a chemically treated carbon bed is a different category of machine. This is the same distinction the purifier community makes when it argues that carbon weight in pounds, not the presence of a carbon filter, is what you should be comparing.

UltraHEPA and the 0.003 Micron Claim

Capturing 99.99 percent at 0.003 microns is an impressive number and an honest one for the ultrafine fraction. The practical caveat is that ultrafine particles in a home are usually a smaller share of total particulate load than fine PM2.5, so the improvement over a 0.3 micron True HEPA is real but incremental in everyday terms.

What matters more here is that the stage does not clog as fast on heavy particulate days, which means the unit keeps its rated performance through a smoke event instead of degrading exactly when you need it most.

Sensor Response and Filter Economics

PM2.5 sensors drive the color-coded AIRDOCTOR HALO display, and Auto Mode adjusts fan speed and activates Boost when readings climb. Owners with lung disease in high-AQI areas report meaningful improvement, and the Auto response to cooking fumes is one of the most common points of praise.

The filters are the problem. Carbon is replaced every six months and UltraHEPA every twelve, both expensive, and the filter indicator has to be reset manually. Owners with FSA or HSA accounts can use pre-tax dollars, which softens the hit considerably for many households.

AIRDOCTOR AD3500 Air Purifier customer photo 2

Who It Is Not For

It is not for a small bedroom, both because of the 24 pound cabinet footprint and because you would be paying for filtration you will never use at that room size. It is also the wrong choice if you are budget sensitive over a five-year horizon, since the two-stage filter schedule is the most expensive to maintain here. At a 4.7 star average from 471 reviews, the rating is excellent but the review base is far thinner than the Levoits, and we weight that.

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8. Air Oasis iAdaptAir 2.0 – The Quietest Unit and the Longest Filter Life

QUIETEST FOR BEDROOMS
Air Oasis iAdaptAir 2.0 H13 HEPA Filter Air Purifier Reduces 99% of Viruses, Mold, Dust, Smoke, Pollen & Odors Quietest on The Market WiFi Compatible 3,975 Sq Ft of Clean Air

Air Oasis iAdaptAir 2.0 H13 HEPA Filter Air Purifier Reduces 99% of Viruses, Mold, Dust, Smoke, Pollen & Odors Quietest on The Market WiFi Compatible 3,975 Sq Ft of Clean Air

★★★★★★★★★★4.5 / 5

530 CFM CADR

H13 HEPA to 0.05 microns

5-stage with UV

Filters last up to two years

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Pros

  • 530 CFM CADR covers 3975 sq ft in one hour or 795 sq ft at 5 air exchanges
  • Five-stage system adds UV light
  • a silver ion screen and bi-polar ionization to the H13 HEPA and carbon
  • Medical-grade H13 HEPA filtration down to 0.05 microns
  • Exceptionally quiet operation with a sleep mode that dims the indicator
  • Filter life of up to two years
  • Removable Wi-Fi chip for EMF-sensitive users

Cons

  • Wi-Fi app does not work as advertised and cannot control the unit
  • Filter changes are priced as an expensive long-life set
  • Tall 37 inch tower is the largest footprint in the roundup
  • Smallest variant covers only 1325 sq ft so sizing must be checked carefully
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The Air Oasis iAdaptAir 2.0 is the most feature-rich unit in this group and the one we would put in a bedroom if bedroom silence is the deciding factor. It runs at 530 CFM CADR, covers 3975 square feet in one hour, or 795 square feet at a full 5 air exchanges per hour, which is the highest realistic air-change figure anyone in this roundup publishes for a residential unit.

Filtration is a five-stage stack: medical-grade True HEPA rated H13, carbon filtration, a silver ion screen, bi-polar ionization, and a UV light. Reported reduction reaches 99 percent for smoke, dust, pet dander, pollen, mold, bacteria, and viruses, and particles are captured down to 0.05 microns.

Air Oasis iAdaptAir 2.0 H13 HEPA Filter Air Purifier Reduces 99% of Viruses, Mold, Dust, Smoke, Pollen & Odors Quietest on The Market WiFi Compatible 3,975 Sq Ft of Clean Air customer photo 1

The Best Filter Economics in the Roundup

Filter life of up to two years between changes is the standout number here, and it is the reason the total cost of ownership can work out favourably despite a high purchase price. If you are the type of owner who will actually keep the unit running, the amortised filter cost per year can land below units with far cheaper cartridges.

That assumes you will not run it on high constantly in a dirty environment. Owners in wildfire smoke report noticeable improvement during those events, and in that scenario you would want to move the unit, not just run it harder.

What the UV and Silver Ion Stages Do

The UV light stage adds an antimicrobial layer on top of particle filtration, and the silver ion screen and bi-polar ionization stages are included for the same purpose. These are additive, not substitutes: the H13 HEPA and carbon stages still do the heavy lifting on particles and gases.

Because it includes bi-polar ionization, this unit sits in the same category as the Coway Mighty for anyone who has decided to avoid ionization on principle. As with the Coway, we would want your clinician’s input rather than making that call for you.

The Wi-Fi Problem, Stated Plainly

The single most common owner complaint at this price point is that the Wi-Fi app does not function as advertised. Reviewers report it does not mirror the on-device readings and cannot actually control the unit, which means the smart features are effectively decorative. The removable Wi-Fi chip is a genuine accommodation for EMF-sensitive users, but the app problem is real and you should buy this machine knowing the app will not do much.

At 37 inches tall and 20 pounds, it is also the largest footprint here. The smallest variant covers only 1325 square feet, so double-check sizing against the room before committing, and note the 4.5 star average comes from only 181 reviews, the thinnest base in the roundup.

Air Oasis iAdaptAir 2.0 H13 HEPA Filter Air Purifier Reduces 99% of Viruses, Mold, Dust, Smoke, Pollen & Odors Quietest on The Market WiFi Compatible 3,975 Sq Ft of Clean Air customer photo 2

Who It Is Not For

It is not for anyone who wants a working smart-home integration, since the app does not deliver on its promise. It is not for a small bedroom either, because a 37 inch tower in a 1325 square foot coverage class is a lot of furniture for a space that size. And if the upfront filter set cost is a barrier, a smaller high-CADR machine is the smarter entry point.

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How to Choose an Air Purifier for COPD: The Four Criteria That Decide Everything

After running these eight machines, we settled on a shortlist of criteria that reliably separate the units worth owning from the units that are merely marketed at lung health. The four that follow are the ones we would use, and they matter in this order.

1. True HEPA Filtration, and What 99.97 Percent at 0.3 Microns Means

A true HEPA filter removes 99.97 percent of airborne particles at 0.3 microns, which is the worst-case size for the most penetrating particle. Anything genuinely rated H13 or above should publish that number, and ideally publish an AHAM Verifide CADR to go with it. Anything selling you a washable or washable-looking filter is not a HEPA filter at all.

Smaller units often quietly specify HEPA-grade performance only in sleep mode. The Core 300-P states its filtration tier for the mode it actually runs in at night, which is honest, but you should always find out which speed a rating belongs to before you rely on it.

2. Activated Carbon in Pounds, Not Marketing Language

Every purifier on this page has a carbon filter. Almost none of them tell you how much. Carbon weight in pounds is the only comparable number, and a few ounces is decorative. If your triggers include cooking fumes, gas stove emissions, wildfire smoke, or paint and cleaning products, a chemically treated carbon bed like the AIRDOCTOR’s potassium permanganate stage is worth the extra cost.

Be skeptical of the phrase medical-grade, which is an unregulated marketing term with no certification attached to it. It appears on marketing pages for products that are entirely ordinary, and it should carry zero weight in your decision.

3. Skip Ionizers: The Ozone Question for COPD

Ozone is a respiratory irritant. It triggers cough, wheeze, and bronchospasm, and it inflames exactly the kind of airway that COPD has already damaged. This is the one place in this article where we will not negotiate: if you have COPD, do not buy an ionizer, a plasma purifier, or any unit that sells itself on generating negative ions.

Look for CARB Type II compliance, which is the California standard for low-emission air cleaners, and treat any unit that advertises ion generation as disqualified regardless of its filters. Where a machine includes a bipolar ionization stage as part of a mixed filtration path, like the Coway Mighty and the Air Oasis iAdaptAir, understand the trade-off and make the call with your clinician.

4. CADR and Air Changes per Hour, Not Room Size Marketing

Room size on a box is a single-air-change figure, and single air change is nowhere near enough for a chronic lung condition. We aim for four to five air changes per hour in the room where you spend the most time, which for most people is the bedroom. Take the AHAM Verifide smoke CADR, multiply the room volume, and work out the actual number of air changes before you buy anything.

Do the arithmetic. A 14 by 14 bedroom with an 8 foot ceiling is 1568 cubic feet. A unit at 143 CFM delivers roughly 5.5 air changes per hour there. A unit at 60 CFM delivers just over 2. If a listing only quotes square feet, assume one air change and divide your own room size accordingly.

What the American Lung Association Actually Recommends

The American Lung Association’s guidance is about filter type rather than brand. It points people with chronic lung disease toward portable HEPA filtration, which works best as a three-stage system with a particle filter to catch large debris, a HEPA filter for fine particles, and an activated carbon filter for gases and odors. It also consistently advises that ventilation and source control still matter and that no purifier replaces them.

The other consistent theme in that guidance is dose. Run it continuously rather than in bursts, and place it in the room you occupy most. Nothing about a brand name appears in the recommendation, which is why we have ranked these on verified CADR, carbon weight, and ozone-free construction instead.

Noise at the Speed You Will Actually Run

The 24 decibel sleep mode of the Core 300-P and the 23.5 decibel lowest setting of the Winix 5520 are the figures that matter for sleep. Noise at maximum speed is nearly irrelevant to a COPD user, because nobody plans to breathe through a Turbo setting all night. Evaluate the low-speed number.

Continuous run time also matters for how the noise accumulates. A unit you switch off at bedtime because it is too loud simply does not get used, and an unused purifier removes nothing.

Filter Cost and Cadence Over Five Years

This is where budget air purifiers quietly become expensive. Genuine replacement media is proprietary, and the annual cost of filters can exceed the cost of the unit within two years. The Air Oasis iAdaptAir is the counterexample, with a filter life of up to two years that can make total ownership favourable despite a high purchase price.

Our rule is to price the five-year filter cost before the unit cost. A cheap purifier with a 3000 hour filter rated at four to five months is not cheap. If you buy a unit expecting to move it between rooms, factor that time in as running hours.

Air Purifier vs Humidifier for COPD: Two Different Jobs

This is the question that comes up more than any other in lung health forums, and it is the one most product pages ignore. The answer is that they do completely different things, and you may need both, but you should never confuse one for the other.

An air purifier removes particles and gases from existing air. A humidifier adds moisture to existing air. Neither creates air and neither treats COPD. If your air is dry and you are coughing on waking, a humidifier may help. If your air contains smoke, dust, dander, or VOCs, only a purifier touches it.

The trap is over-humidifying. Households run humidifiers to silence nighttime cough and end up with 60 percent indoor humidity, which is the range where mold grows, and mold spores are themselves a COPD trigger. Aim for 40 to 50 percent relative humidity and get a cheap hygrometer so you are guessing less. If you use a nebulizer, follow the manufacturer’s humidity guidance, because published research on asthma and COPD notes that incorrect humidifier use can worsen airway obstruction.

Our recommendation for a COPD household is a separate, small, cool-mist or ultrasonic humidifier with a hygrometer, kept in a room the purifier is also serving, and never run overnight without monitoring. Anything scented, including scented essential oil warmers, should be off. Fragrance is a respiratory irritant and the entire reason you bought the purifier.

If you have a basement or a lower level that floods or holds humidity, the purifier alone will not solve it. Our basement purifier guide covers that environment specifically, where mold management matters as much as particle filtration.

These are the questions that come up repeatedly in respiratory forums and clinician Q and A threads, answered directly. If your question is not here, ask your care team, because the honest answer for anything individual is a personalised one.

Frequently Asked Questions

What’s better for COPD, an air purifier or a humidifier?

They do different jobs. An air purifier removes particles and gases such as PM2.5, dust, pet dander, smoke and VOCs, while a humidifier adds moisture to the air. Neither treats COPD. Most COPD households benefit from both, but keep indoor relative humidity between 40 and 50 percent, because over-humidifying promotes mold growth and mold spores are themselves a trigger.

What air purifier does the American Lung Association recommend?

The American Lung Association recommends portable HEPA filtration rather than any specific brand. It points toward a three-stage system: a particle pre-filter for large debris, a true HEPA filter for fine particles, and an activated carbon filter for gases and odors. Its guidance also stresses running the unit continuously in the room you use most, and keeping up source control and ventilation, which no purifier replaces.

Which air purifier is best for people with COPD?

The Levoit Core 300-P is our best overall pick for a bedroom, with an AHAM Verifide 143 CFM smoke CADR, 99.97 percent filtration at 0.1 to 0.3 microns, and a 24 decibel sleep mode. In a room larger than about 220 square feet, choose the Levoit Core 400S-P at 231 CFM smoke CADR, or the Honeywell HPA304 for very large open rooms.

Do air purifiers actually help COPD symptoms?

They reduce exposure to indoor triggers, which is the part of COPD management you control directly. Research, including work cited out of Johns Hopkins, links fine particulate and indoor air pollution exposure to airway inflammation and to cardiovascular and respiratory markers. That said, no purifier improves lung function or reverses damage, and evidence for reduced exacerbation rates specifically is thinner than the marketing implies. Treat a purifier as trigger management, not treatment.

Can I use an ionizer air purifier with COPD?

No. Ionizers generate ozone as a byproduct, and ozone is a respiratory irritant that provokes cough, wheeze and bronchospasm, which is exactly the reaction a COPD patient cannot use. Look for CARB Type II compliant units and skip anything that advertises negative ions. The Coway Mighty and Air Oasis iAdaptAir include a bipolar ionization stage inside a mixed filtration path, so if you want a purely mechanical path, choose the Levoit, Honeywell, or Winix instead.

How often should I run an air purifier with COPD?

Continuously, and in the bedroom first. Most people with COPD spend their worst hours in the bedroom, and a purifier switched off overnight does nothing for them. Run it on low or sleep mode at night to keep noise down, raise the speed when cooking or when outdoor air quality is poor, and leave the door closed so the unit is not trying to clean the whole house. If someone in the home is frequently ill, replace filters on a shorter schedule than the manual states.

Which air purifier do Redditors recommend?

On the r/AirPurifiers community, the consensus for VOC and smoke problems is that IQAir and Austin Air lead the category, with Alen named as the more affordable alternative because of the amount of activated carbon in the 45i and 75i units. The same forum’s most repeated practical advice is to compare pounds of carbon rather than the mere presence of a carbon filter, and to size by CADR instead of the square footage on the box. Owners on r/Asthma report the clearest perceived benefit on smoke and wildfire days.

The Verdict: Which Air Purifier for COPD Is Right for You

Pick the Levoit Core 300-P if your priority is a bedroom machine you can sleep beside, because the 24 decibel sleep mode and 143 CFM verified CADR are the combination we could not improve on for the money. Move up to the Levoit Core 400S-P if your room runs past roughly 220 square feet or you want live PM2.5 data on the front panel. Choose the Honeywell HPA304 for a large open room where high air changes per hour and flat-to-the-wall placement matter, and where a decade-long service record is worth having.

Choose the Winix 5520 for the finest particle capture with a built-in sensor and the quietest low setting. Go with the Coway Mighty for pet and cooking odor duty and a longer warranty, understanding it contains a bipolar ionization stage. Pick the Medify MA-112 PRO for an open floor plan where one machine has to do the whole level, and the AIRDOCTOR AD3500 when gas, VOCs, or wildfire smoke are the trigger. The Air Oasis iAdaptAir 2.0 is the quietest option with the longest filter life, provided you do not expect its app to work.

Whatever you choose, run it continuously, size it by CADR rather than square footage, replace filters on a schedule you set before you need to, and keep it away from ionizers and scented aerosols. And talk to your pulmonologist before you buy, because for anyone managing COPD, the purifier is one part of a plan their care team should know about.

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